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February 01, 2013 (Vol. 33, No. 3)

Tying Up Loose Ends in Cell-Line Development

  • As cell-line optimization continues to push bioprocess productivity limits, several “loose end” issues persist. These include the use of design of experiment in clone selection, viral contamination, automation, and cell-level engineering. Automation plays an increasingly significant role in cell-line development, particularly during clone screening and selection. When paired ...

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