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November 15, 2005 (Vol. 25, No. 20)

Tissue Models Boost Drug Discovery Efforts

Eliminating Toxic and Ineffective Compounds at an Early Stage

  • R&D costs for each new drug on the market are estimated to be $800 million. Traditional molecular screening, although high-throughput, does not provide information about the effects of test compounds on cellular functions. Also, 2-D cell cultures do not accurately reflect in vivo drug responses. Therefore, as demonstrated ...

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