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TechNote: Antibiotic-Free Systems for Production
Bypassing the Expression of Exogenous Site-Specific Recombinases
- The use of antibiotic resistance markers to select for a successful genetic modification, such as a chromosomal insertion or a plasmid transformation, is common practice. However, with increasing stringency in manufacturing regulations it is essential to ensure that the end product contains no antibiotics and no genes for antibiotic ...
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