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September 01, 2011 (Vol. 31, No. 15)

Targeted Resequencing Hits Bull's Eye

Technology Owes Rapid Growth to Potential in Biomedical Research and Clinical Medicine

  • In recent years, next-generation sequencing approaches have generated unprecedented advances. With over 2,000 genes linked to at least one disease-relevant mutation, DNA sequencing has assumed increasingly important clinical relevance. Nevertheless, multiple considerations still make it impractical to routinely sequence large numbers of eukaryotic genomes. Enrichment for specific regions ...

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