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April 01, 2011 (Vol. 31, No. 7)

Taking Cell Cultivation to Another Level

New Optimization Strategies Help to Make a Good Thing Even Better

  • To borrow an expression from the world of competitive chess, “every Russian schoolboy knows” what factors affect biomanufacturing product yield and quality. Start with a robust cell line, select for viability and expression level, then experiment around media, feed, and bioreactor/fermentor conditions. Throw in some analytics and you’re set. ...

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