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December 01, 2005 (Vol. 25, No. 21)

Strategies to Move Beyond Target Validation

Targets and Druggability for Small and Large Molecule Drugs

  • Genomics and proteomics have made thousands of potential targets available to drug discovery researchers. These researchers utilize a number of target identification and validation technologies, ranging from comparative genomics to gene expression profiling to RNA interference (RNAi) to animal models, in order to sort through the host of potential ...

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