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May 01, 2013 (Vol. 33, No. 9)

Separation of Therapeutic Biomolecules

Mixed-Mode Chromatography, Layered Bead Designs, In Silico Modeling Used at Large Scale

  • Hydrophobic-interaction chromatography and reversed-phase chromatography (HIC/RPC) for large-scale separation of proteins was the focus of a series of talks at Tosoh Bioscience’s recent “HIC/RPC Bioseparation Conference: Advancements, Applications and Theory in Downstream Processing.” The program provided a balance of theory, practical applications, scale-up tools, and state-of-the-art resins and ...

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