includes a list of ion exchange resins that are widely used for decolorization, but other similar products are available.
A filtered, crude vancomycin broth was adjusted to pH 8, and the broth was then pumped over a column of Amberlite FPA40 Cl using a Rainin Rabbit Pump. The column effluent was monitored with a Linear Model 200 detector (Grace Davison Discovery Science) and fractions were collected in one tube every five minutes using a Gilson 201 Fraction Collector. The experiment involved a column of 2.0 cm ID x 30 cm L and a flow rate of 1.63 mL/minute (1 CV/Hr). Detection was performed with a Thermo Fisher Scientific Biomate 3 Spectrophotometer at 400 nm.