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September 01, 2005 (Vol. 25, No. 15)

Prion Disease Mechanisms and Activation

Finding Faulty Proteins

  • Transmissible spongiform encephalopathies (TSEs), the diseases caused by proteinaceous infectious particles, or prions, comprise a group of fatal neurodegenerative diseases that take their name from the holes they cause in the brains of susceptible animals and humans. Animal forms of prion diseases occur in sheep and goats (scrapie), ...

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