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January 01, 2014 (Vol. 34, No. 1)

Predictive In Vitro Assay Trend Grows

  • Lack of safety or efficacy continues to impact the failure rate for compounds entering clinic trials, implying that the current preclinical decision-making paradigm is not sustainable. Animal models and commonly used in vitro assays are simply not predictive of human response. More life-like cell-based models are emerging, and ...

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