The deployment of Benchware Notebook to several hundred global users at Schering (www.schering.com) took place in the context of a larger informatics solution, the Enterprise Chemical Information Management System (ECIMS).
Built on the Benchware Notebook platform, the ECIMS solution provides support for planning and synthesis of compounds and handles the logistics of compound management through additional compound registration, inventory, and ordering functionality. ECIMS allows researchers to share critical research data and manage research projects.
To enter a new experiment in Benchware Notebook, a Schering user starts with a template notebook page. The components of the template page can be dictated by business rules, and dynamically customized and repositioned by the user to suit individual workflows. New customized page components can also be defined and added by a system administrator, and can be created to be domain-specific to areas such as medicinal chemistry, parallel chemistry, high-throughput chemistry, genomics, screening, ADME, and toxicology. Auto-calculation functionality within a Benchware Notebook page allows Schering chemists to determine experimental factors such as stoichiometric amounts and molecular weights (Figure).
In addition to using Benchware Notebook to plan and document experiments, Schering scientists take advantage of features within the application to collaborate with colleagues throughout the organization.
With all entered data stored in an underlying Oracle database, Benchware Notebook users are able to dynamically search notebook pages across the organization. Searches can be done by using conventional alphanumeric search terms as well as by using more complex chemistry-centric search terms, allowing users to search by compound structure.
Researchers at Schering use these features to study reactions produced by colleagues to gain new insights into their own plans, thereby saving valuable time and sparking innovation.