Plug-and-play products may help address the need for operational efficiencies in the industry. Self contained, fast to implement process setups extensively based on disposable solutions are already in reach for most unit operations. Tanks can be replaced with bags, hard piping can be replaced with flexible tubing, disposable pump heads and detection cells can be used, and both cleaning and validation efforts can be reduced.
A significant challenge resides in the integration of such unit operations and in finding the right connectivity among, what is today, still a rather uncoordinated offering. ReadyToProcess™ products include both complete solutions engineered for flexibility as well as single-use devices and components. With minimal installation times and mobile hardware, the flexible and modular nature of ReadyToProcess enables a quick capacity deployment in the event of an emergency such as a pandemic outbreak.
This suite of products embraces single-use cell culture technology and includes Wave bioreactor systems and mixers, fluid handling, filtration, and chromatography solutions. ReadyToProcess filters include cleanroom-to-cleanroom, single-use cartridges and assemblies for both aseptic cross flow and sterile normal flow filtration (NFF) operations.
ReadyToProcess NFF devices are produced according to the medical devices standard (ISO 13485), provided sterile and gamma irradiated. Both filtration solutions come fully certified, either as stand-alone units or as part of full assemblies.
ReadyToProcess chromatography products include cleanroom-to-cleanroom columns, available in several sizes from 2.5 L to 20 L bed volumes. This range of modular columns is packed with resins designed to meet the demands of modern chromatography. The portfolio currently includes high-flow Capto™ Q (strong anion exchanger), Capto S (strong cation exchanger), or Phenyl Sepharose™ 6 Fast Flow for hydrophobic interaction chromatography.
These columns are fully certified and tested high-performance modules, available for developmental work and clinical-scale manufacturing, enabling smooth scale up, rapid project changes, free from the risk of cross-contamination and packing failures.