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July 01, 2017 (Vol. 37, No. 13)

Optimizing the Delivery of Peptide-Based Therapeutics

Despite Processing Advantages, Peptides Pose Serious Delivery Challenges

  • Interest in nonnatural peptide drugs has waxed and waned over the past 30 years. The science has been fascinating, but delivery and pharmacokinetic issues remain. During the 1990s, Affymax popularized libraries of short peptides immobilized on inert substrates, but these peptides never led to novel therapeutic molecules or ...

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