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March 15, 2010 (Vol. 30, No. 6)

miRNAs' Therapeutic Potential

Scientists Scrutinize Promising Molecules as Potential Drug Targets and Biomarkers

  • MicroRNAs (miRNAs) finely regulate gene expression and play an important role in various cellular processes, including cell growth, differentiation, proliferation, and apoptosis. To date, more than 5,000 of these endogenous, noncoding single-stranded RNAs have been identified. miRNAs act through binding to complementary mRNA sequences, thereby preventing their translation into ...

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