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Mar 15, 2008 (Vol. 28, No. 6)

Metabolic Monitoring Enhances Production

Method Can Improve Success Rate of Fermentation Process Development & Transfer

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    Figure 3

    Figure 3 shows an example of using the described strategy to automatically link the batch-growth phase and the following fed-batch phase. The auto-feed start has proven to work seamlessly, allowing for flexible study plans, multiple parallel studies, and automatic process control that is scale independent. It can be integrated into a manufacturing-scale protocol used as an assisting tool to help supervise processes.

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