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April 15, 2008 (Vol. 28, No. 8)

Managing Data from Next-Gen Sequencing

Tremendous Volume Can Be Handled by Tools Available Now; Complexity Is Another Matter

  • Using novel sequencing chemistries, microfluidic systems, and reaction-detection methods, next-generation sequencing vendors offer 100- to 1,000-fold increased throughput and 100-to 1,000-fold decreased cost as compared to conventional Sanger DNA sequencing. Where high-throughput sequencing was previously limited to top sequencing centers, these new instruments are bringing large-scale sequencing as a ...

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