“Chemspeed introduced numerous disruptive technologies in laboratory automation workflows,” says Michael Schneider, senior vp, business development. “Our Object Oriented Workflow Design is the foundation of all our product lines. By combining independent, functional Shuttles (sample carrier) and Objects (processing workstations) we created a new workflow paradigm that allows to process samples in parallel and sequential fashion. This flexible design supports practically unlimited variations of workflows.”
Each object is an independent “machine”, capable of receiving inputs, processing data, and sending outputs to other objects. Chemspeed’s modular objects are connected by a production-proven track system, carrying up to 100 shuttles. Each shuttle carries its own processes and interacts differently with “objects” along the track.
“This makes the workflow more robust,” continues Schneider. “If one shuttle fails for whatever reason, the others continue on.” The key to designing object-oriented workflows is to carefully identify all the required process steps, to connect them in a logical fashion, and to establish input and output parameters.
Another enabling key element of Chemspeed’s platforms is the flexible exchangeability of the more than 40 robotic tool features. Akin to a swiss-army knife, the unique robotic arm is able to accommodate substance handling, action, or analysis, including gravimetric dispensing, homogenization, ultrasonic dispersion, capping, and many others. These tools can be seamlessly exchanged during the run, providing additional flexibility to workflow design.
Pharmaceutical compound management fits perfectly in such workflow. The processes may include compound retrieval, removal of screw caps, adding of solvents, microdispensing, barcoding, quality assurance analysis, and return to storage. Chemspeed perfected gravimetric dispensing of solids, liquids, and viscous liquids.
Upcoming SWILE dispensing technology is specifically positioned for compound management. Chemspeed’s SWILE supports the “many-to-many” dispense mode and is capable of gravimetrically dispensing sub milligram quantities of compounds with a wide range of consistency, from viscous oils via waxy components to solids. Thanks to an automatically exchanged disposable all glass dispense “tip”, cross-contamination is completely eliminated.