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Interrupting Protein-Protein Interactions
New Methodologies Seek to Find, Map, and Ultimately Disrupt These Processes
- Most proteins including mutated, disease-causing ones do their work as part of multiprotein complexes. Thus, sites of protein-protein interactions would seem to be optimal targets for drug discovery. Of course, this is not as simple as it sounds; researchers have been reluctant to target protein complexes as the average ...
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