Biotherapeutics may take the form of antibodies, antibody fragments, or other recombinant proteins. Biacore A100 enables interaction analyses of multiple samples with multiple interactants, facilitating early selection during screening phases, reducing cost and time, and enabling better decisions to be made regarding candidate selection.
Stable temperature control makes Biacore T100 well-suited for studying interactions at physiological temperature, optimizing the predictive value of the binding data obtained for downstream in vivo testing and clinical use. The high information content data provided by both systems also facilitates critical decisions regarding dose and administration efficacy.
From the earliest stages of discovery through to development and quality control, it is important that laboratory practices comply with regulatory requirements. Biacore T100 and Biacore A100 comply with the FDAs 21 CFR Part 11 Rule and are designed for use further downstream in industry sectors that are subject to strict GLP/GMP/GCP regulatory requirements.
Biacore C is a system dedicated for GxP-compliant, rapid concentration measurements required from preclinical development through to quality control. Results are used to check process control and for batch-release assays.