Molecular Devices’ new SpectraMax® i3 multimode microplate reader platform features standard spectral absorbance, fluorescence, and luminescence detection capabilities. The modular design facilitates the addition of other detection capabilities and the option to add on the SpectraMax MiniMax™ Imaging Cytometer.
Bio-Rad’s NGC™ chromatography system is a modular, readily expandable, and upgradable instrument that incorporates all of the necessary components in one unit, with magnetic surfaces throughout. The company’s configurator tool helps customers design a customized system to meet their application needs.
The 404Pi™ phase-based surface plasmon resonance (SPR) instrument is the first product from BiOptix. Designed with an automated multi-injector (4 injectors/4 parallel flow cells) fluidics system to enable high-throughput, label-free kinetic measurements for molecular interaction analysis with high sensitivity, the instrument can measure protein-protein or protein-small molecule interactions.
An agreement between Advanced Cell Diagnostics (ACD) and The Johns Hopkins University’s Sidney Kimmel Comprehensive Cancer Center centers on the use of the company’s RNAscope® digital pathology analysis software for detecting and quantifying RNA molecules in a cell. ACD and Definiens recently initiated an early access program for the RNAscope SpotStudio™ technology for quantitative in situ RNA biomarker analysis.
EZ DNA Methylation™-Lightning kits from Zymo Research for bisulfite conversion of DNA for methylation analysis require only the addition of the Lightning Conversion Reagent to a 100 pg–2 µg DNA sample. Zymo also showcased its RNA Shield™ reagent, which lyses cells and stabilizes intact RNA, protecting it during transport or storage at ambient temperature.
Norgen Biotek featured its Stool Nucleic Acid Collection and Transport Tube, which stabilizes DNA and RNA for transport at ambient temperature, and its Stool DNA Isolation kit for simultaneous isolation of bacterial and host DNA.
When PerkinElmer launches its new RediFect lentiviral particles, customers will be able to use them to transfect their own cell lines with Redluc firefly luciferase and other bioluminescent and fluorescent reporters. The company’s new GFR-Vivo 680 imaging product is an inulin-based infrared fluorescent agent for obtaining noninvasive measurements of the glomerular filtration rate in vivo to assess animal models of kidney disease, dysfunction, and drug toxicity. It allows for kidney function assessment as part of drug safety studies performed early in drug discovery and makes it possible to assess the efficacy of a drug candidate and its potential for kidney toxicity in the same animal study.
Ingenuity Systems featured the spring release of its flagship IPA software for analyzing and integration of omics data. New features include BioProfiler for identifying genes causally related to a disease or phenotype with the potential to be drug targets or targets for minimizing toxicity. IPA’s new Causal Network Analysis uses data on changes in gene expression to generate hypothetical regulatory networks that may have a role in a disease or phenotype of interest.