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May 15, 2013 (Vol. 33, No. 10)

Harnessing the Power of Kinase Inhibitors

  • The ~600 kinases that make up the human kinome comprise a group of exciting druggable targets that can be modulated using small molecule or monoclonal antibody approaches. There are currently 15 FDA-approved kinase inhibitor drugs, yet there remains much uncapped potential, as the biological function of ~90% of ...

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