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Harnessing Nuclear Receptors
Therapeutics in Development Aim to Enhance Selectivity and Reduce Potential Side Effects
- Nuclear receptors drive many critical processes ranging from metabolism to reproduction by serving as ligand-activated transcription factors. They also represent a lucrative area for drug discovery as evidenced by current therapies utilizing glucocorticoids for asthma, estrogens for hormone-replacement therapy, and retinoids for acne. Current efforts continue to take ...
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