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June 15, 2006 (Vol. 26, No. 12)

Going a Label-Free Route with Biosensors

New Technologies for Calorimetry and SPR Aim to Transcend the Drawbacks to Labels

  • Molecular labels have enabled many scientific advances that would not otherwise have been possible. However, labels have drawbacks. They disrupt the accurate measurement of kinetic constants, particularly binding equilibria, and problems, such as antibody cross reaction or impure solutions, can occur. Many companies are developing label-free biosensors for biotechnology ...

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