Ready-to-go vs. Customizable
Thermo Electron (www.thermo.com/ informatics) recently introduced Darwin LIMS, its latest commercial off-the-shelf (COTS) LIMS.
Darwin LIMS is designed and developed specifically for pharmaceutical R&D and manufacturing quality control. The system handles, but is not limited to, formulation development, stability studies, and dissolution testing, says Joe Peden, director of marketing and product management for Thermos informatics business.
Darwin tracks samples and production batches. Since it is based on COTS functionality, it can be deployed with the minimum of customization. This reduction in customization reduces implementation risk and total cost of ownership of the system.
Thermos LIMS portfolio also includes Watson LIMS for bioanalytical labs, Galileo LIMS for in vitro ADME research, and Nautilus LIMS for R&D, particularly in biotech. Watson streamlines bioanalysis of compounds for critical nonclinical studies that are conducted prior to human studies.
LabVantage Solutions offers three Sapphire solutions for pharma and biosciences that all operate on the same thin-client, enterprise platform that applies to R&D and QC labs. The companys Sapphire life science R&D solution includes experimental design and management functionality that allows end-users to design experiments using a graphic interface, execute tasks, and capture data, according to LabVantange.
The solution goes beyond just data management, according to a company spokesperson, because it also records metadata associated with the experiment, task, and sample.
According to LabVantage, the Sapphire Quality Management LIMS tracks samples and provides full traceability for raw materials testing and quality management, and, through automated workflows and specification checking, provides prompt feedback to correct any problem. The Sapphire BioBanking solution is aimed at repository or biospecimen management.
Pharmaceutical companies have thousands of clinical samples from patient registries or clinical trials that they use for drug discovery and personalized medicine. The BioBanking module stores, locates, and tracks biospecimens, along with their aliquots and derivatives, explains Kasner.
Moreover, it provides easy access to vital biospecimen data such as genomic, proteomic, and phenotypic information that can be utilized during the discovery process for biomarker research, phamacogenomics, and pharmacoproteomics studies.