The final test of the purified analytes is how they perform in downstream analysis. During testing, the isolated DNA, RNA, and denatured proteins were found to be entirely compatible with end-point PCR, sequencing, real-time PCR, microarray analysis, SDS-PAGE, Western blotting, 2D-DIGE, and LCMS. DNA, RNA, and protein purified using the triplePrep kit were compared with that purified using single-analyte purification methods. In all cases, the data collected from triplePrep samples gave results directly comparable to, or better than, those from traditional approaches. For example, protein analysis was conducted by 2-D DIGE analysis against the recommended 2-D DIGE reference sample (Figure 2).