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January 01, 2014 (Vol. 34, No. 1)

Delivering Nucleic Acids into Cells

  • Whether one is elucidating biological mechanisms, correcting a faulty gene, or modulating gene expression, artificially introducing nucleic acids into cells requires an efficient and nontoxic delivery method. Transfection (placing nucleic acids into cells by nonviral methods) and transduction (utilizing viral vectors) are fundamental tools for getting the payload ...

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