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July 01, 2008 (Vol. 28, No. 13)

Conquering RNAi Delivery Challenges

Innovative Solutions Include Nanoparticles and Stabilized Compounds

  • RNA interference (RNAi) is making great strides as an indispensable strategy for target-specific knockdown of gene expression. Emerging second-generation technologies represent advances in RNAi design, efficiency, and efficacy. Yet, daunting obstacles remain, such as how to deliver RNAi compounds to the right targets in the right amounts. Two ...

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