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October 15, 2012 (Vol. 32, No. 18)

Confronting Scaleup Challenges Head On

  • Despite new heights of process characterization and knowledge, scaleup still can befuddle the most experienced of bioprocessors. Wei Chen, Ph.D., chief scientist at Phage Pharmaceuticals, believes that a disconnect between early-stage R&D and manufacturing—a defect that has persisted since biotech’s earliest days—is one culprit. “Companies have come ...

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