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April 01, 2005 (Vol. 25, No. 7)

Chemical Genomics Facilitates Finding Targets

Important New Mechanisms and Protein Targets Have Already Been Uncovered

  • Chemical genomics, using small molecules to elucidate gene, protein, and pathway functions, in a cellular context, by modulating activity of gene products, whether known molecular targets or gene products of unknown identity, is a powerful method for target validation and complements other methods since it operates on the protein, ...

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