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November 15, 2010 (Vol. 30, No. 20)

Capitalizing on Cell-Signaling Advances

Revelation of Potential Intervention Points for Therapeutic Development on Upswing

  • The development and clinical application of drugs that target intracellular signal-transduction pathways has profoundly changed the treatment of human cancers. Tools enabling complex pathway analysis, particularly those that can identify critical regulatory post-translational modifications, continue to facilitate discovery of novel targets for cancer therapeutics and provide insights into drug-resistance ...

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