Physicians depend on tests for cancer biomarkers at various disease stages to help them diagnose, monitor, predict treatment or prognosis, and also predict risk for their patient’s particular cancer. Laboratory testing for cancer biomarkers spans multiple clinical detection platforms and includes traditional mainstays like immunoassay, immunohistochemistry, and flow cytometry and also the newer molecular-based platforms like PCR, microarrays, and sequencing.
Frost & Sullivan sized the U.S. cancer biomarker testing market at $7.86 billion in 2011 and expects this to reach $11.46 billion by 2017 with positive growth driven by incorporation of companion diagnostics (KRAS, EGFR, BRAF V600E) into clinical guidelines and then rapid development of clinical next-generation sequencing (NGS).
The molecular-based cancer biomarker testing segment, including single-mutation companion diagnostics, multiplexed array, and other genomic analysis, were only 4% of total market revenues in 2011, but this will likely reach 9.4% by 2017 from 22.9% annual growth.
A recent Frost & Sullivan analysis of the U.S. cancer biomarker testing market produced a number of predictions about what cancer testing, new test development, and patient management will look like in the future.