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March 15, 2008 (Vol. 28, No. 6)

Applications Broaden for Epitope Mapping

Basic Tool Has Copious Uses in Development of Vaccines and Protein Therapeutics

  • Epitope mapping, initially a basic-science tool for understanding the 3-D interactions between antigens and antibodies, is now being extensively employed to develop new therapeutics. In vaccine technology, especially, scientists in academia and biotech firms have mobilized epitope discovery based on the use of high-throughput antibody screening for rational vaccine ...

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