Additionally, researchers who do not need the advantages of multiplexing, lack the funding to purchase expensive array instrumentation and reagents, focus only on a few analytes, or require high assay sensitivity, continue to use ELISA kits. While the trend toward multiplex proteomic arrays has accounted for a declining growth rate in the overall ELISA market, unless newer platforms dramatically decrease in price and improve on sensitivity levels, the ELISA will continue to maintain a role in research.
Interestingly, ELISA providers have reacted to newer technologies in different ways. Determined to take advantage of the trend toward multiplexing, several companies have stalled expansion of their ELISA kit portfolios over the past five years in favor of focusing resources toward the development of multiplex or other new assay types. Other providers vehemently defend the complementary role of ELISAs to proteomic arrays and continue expansion of their ELISA lines while building multiplex assay portfolios as well.
Smaller companies without the R&D budgets to develop new multiplex assays have sought niche markets to penetrate to circumvent heavy competition. In general, new ELISA product introductions attempt to serve a different market sector than multiplex assays currently reach.