G-Rex: G-Rex Devices have proven to be highly advantageous in applications in which the number of devices used in the application, feeding frequency, the number of pipette interventions, or the use of labor is excessive. Adoptive Cell Therapy is an excellent example of where this advantage is being realized.
The Adoptive Cell Therapy community has made great strides in the use of T cells to advance effective treatment of various diseases. Yet, the ability to move those advances to a larger population has been hampered by the inability of traditional cultureware to produce the large number of cells required for treatment in a simple, efficient manner. Until now, ACT has been forced to rely upon the use of plates, flasks, and bags, which creates a complicated, labor-intensive process. Wilson Wolf’s G-Rex device is intended to break down the barrier to efficient cell production. Data from leading institutes continues to show the power of G-Rex to accomplish this objective for TIL, EBV-CTL, NK, CAR adapted T cells, Tregs, among others.
Importantly, G-Rex has been shown to shorten production duration while simultaneously reducing use of medium, materials, feeding frequency, labor, and complexity. In brief, G-Rex makes Adoptive Cell Therapy practical.
CELLine: CELLine is a versatile tool for culture applications that can benefit from highly concentrated cell secreted product, minimized use of exogenous growth factors, and minimal feeding frequency. CELLine can be used in serum-based and serum-free applications. CELLine CL1000 and CELLine CL350 are designed for suspension adapted cell types, while the CELLine AD is designed for adherent cell types. CELLine CL1000 and CELLine CL350 are routinely used in monoclonal antibody production at most core hybridoma labs because they are so cost effective and easy to use.