1. Molecular Biology
As “Your Gene Company,” OriGene has a broad portfolio of biological reagents and services that are of value to both academic research and industry product development. Utilizing high-throughput technologies in molecular cloning, the human cDNA collection is nearing completion with respect to the NCBI RefSeq curated database of unique human transcripts. Such a comprehensive portfolio of cDNA clones is of particular value to laboratories that wish to move their projects along quickly by purchasing ready-made clones and where time is of the essence in mission critical research. If not immediately available, OriGene’s Blue Heron synthesis service can conveniently provide any gene, any sequence, in any vector, with add-on services of codon-optimization and large-scale DNA purification. The cDNA clone sets can be used for high-throughput functional screening to identify novel players in biological processes.
2. Protein Assay and Antibodies
OriGene’s 9,000 recombinant human proteins produced in human cells are of high value to researchers that are interested in authentic structure. Proteins with correct post-translational modifications (phosphorylation, glycosylation, etc.) are crucial for biologically relevant structure and functional studies. They are also ideal for assay development, small molecule interaction screening, or as antigens for antibody production.
Taking full advantage of the large collection of human proteins, OriGene has created a monthly manufacturing capacity to produce over 300 TrueMAB monoclonal antibodies. Genomic Antibody Technology, a novel antibody development platform, is also employed by OriGene to create over 1,000 antibodies against difficult targets, including multispan membrane proteins and GPCR. Such highly specific antibodies directed against authentic human protein antigens are ideal for critical assay development, especially for Flow, IP, IF, IHC, ELISA, and functional assays.