BIOBASE offers comprehensive solutions to life science researchers. Our databases contain expert-curated biological information that works with included analysis tools for human mutation, gene regulation, and functional analysis to generate maximum value from your experimental data.
BIOBASE’s Genome Trax™ enables you to identify human genome variations of functional significance by mapping your next-generation sequencing (NGS) data to known elements such as disease mutations and regulatory sites. For human gene mutation BIOBASE’s HGMD® Professional provides comprehensive data on human inherited disease mutations to genetics and genomic research. It is widely used in human genetics research, diagnostics, and personal genomics applications.
BIOBASE’s powerful ontology search query system, PROTEOME™, with specialized tools for gene set analysis and pathway visualization, allows scientists working with mammalian, yeast, worm, and plant species to quickly find answers to questions relevant to their research.
Finally, TRANSFAC® and ExPlain™ offer the most comprehensive collection of eukaryotic gene-regulation data in combination with advanced analysis tools. TRANSFAC is a knowledgebase containing data on eukaryotic transcription factors, their experimentally proven binding sites, and regulated genes. Promoter analysis of high-throughput data based on TRANSFAC positional weight matrices is provided in the accompanying ExPlain™ Analysis System, a unique data-analysis platform that combines promoter and pathway analysis tools. ExPlain™ enables you to identify transcription factors affecting gene expression in your microarray and RNA-Seq experiments, as well as predict how they, acting in combination, can induce observed gene expression patterns.
For researchers with specialized needs, we offer custom curation and analysis services. Through custom curation services we apply our expertise in data extraction and management to the topic of interest to you, while through custom analysis services we leverage our experience in data analysis to bring meaning to your high-throughput datasets. Together our products and services help researchers make sense of the overwhelming amount of published and experimental data to identify relations critical to drug and biomarker discovery.