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May 01, 2012 (Vol. 32, No. 9)

Advancing Beyond the Genome with Affinity Proteomics

  • Until recently, the field of disease proteomics was focused on separation techniques coupled with mass-spectrometric identification of proteins. However, technological limitations due to patient-to-patient variability and loss of signal from low-abundance proteins have lead researchers to a different technique: affinity proteomics. Based on the use of capture reagents ...

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