Biotechnology from bench to business

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• ADME/Tox
• Automation
• Bioprocess Scale-Up
• Bioreactors
• Biosimilars
• Cell Culture
• Cell-Based Assays
• Contract Manufacturing
• Gene Therapy
• High-Throughput Screening
• Immunoassay
• Induced Pluripotent Stem Cells
• Informatics
• Liquid Handling
• mAb Production
• Protein Characterization
• Protein Detection
• Protein Production
• Regenerative Medicine
• RNAi/siRNA
• Stem Cells
• Western Blot

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• Insight & Intelligence™

• Tales from the Biotech Crypt: Sam Waksal Is Back in Business
  November 3, 2010
  Former ImClone CEO has started a new firm, made three acquisitions including Three Rivers, and begun licensing.
• Is Avastin Roche’s Achilles Heel?
  November 1, 2010
  Label-expansion efforts have failed, and mAb stands to lose provisional approval in breast cancer.
• Will a Nonautologous Cancer Vaccine Be the Next to Make It Through Approval?
  October 25, 2010
  In the race to mimic Dendreon’s success with Provenge, off-the-shelf products make for attractive opportunities.
• What Comes After Dendreon’s Provenge?
  October 18, 2010
  Success of prostate cancer vaccine has ushered in a wave of autologous vaccine development.
• Innovations in Peptide Structure Pushing Candidates through Development
  October 4, 2010
  Companies are taking aim at otherwise untractable targets.
• Advancing Stem Cell Therapies for Multiple Sclerosis
  January 25, 2010
  UKSCF partners with MS Society to financially support clinical development.
• Big Pharma Adopting Orphan Drug Strategy
  December 14, 2009
  Potential for profitability in small markets is beginning to lure companies away from the failing blockbluster model.
• Obesity Therapies Show Lackluster Efficacy Results
  December 3, 2009
  A potential market of $10 billion annually in the U.S. alone is keeping companies in the race to develop better drugs.
• Confusing Choices for Doctors and Type 2 Diabetes Patients
  October 23, 2009
  Drugs in development and on the market are dogged by serious side effects.
• Clinical Trial Failures Further Signal Pancreatic Cancer’s Intractable Nature
  September 25, 2009
  Researchers need to step out of the gemcitabine box and also take on the development of diagnostics for early detection.
• Market Exclusivity—Paramount in Evaluating Target Companies
  September 22, 2009
  The main related factors are relevant facts, freedom to operate, IP, third-party agreements, and regulatory exclusivity.
• Chasing the Therapeutic Potential of miRNAs
  September 10, 2009
  The spate of deal-making, new company formations, and patent applications have set up miRNAs as the next wave in nucleic acid-based drugs.
• When Is Revenue Not Revenue for Biotech Firms?
  August 25, 2009
  Proposed changes in accounting rules highlight complexity for public companies.
• AIDS Vaccine Development Will Rely on Blind Guesses—At Least for Now
  August 14, 2009
  Past failures from companies jumping on the T-cell bandwagon have borne out the complexity of the virus and prompted renewed thinking.
• Need for Novel Approaches to Treating HIV Still Exists
  July 31, 2009
  As resistance continues to be a problem, firms are trying to exploit characteristics that allow the virus to adapt seemingly endlessly.
• Potential Effects of Pending Biologics Legislation on the Patent Application Process
  July 14, 2009
  While patent reform may get bumped to a later Congress, a resolution to biosimilars law may get passed as part of a healthcare reform bill.
• Top-10 Session Picks for the 2009 BIO International Convention
  April 10, 2009
  Topics cover new science policy initiatives, global financial issues, and novel trends.
• Final Stimulus Package Provides $21.5B for Research
  February 18, 2009
  Biggest winner seems to be the NIH, which will receive $8.5 billion for research grants.
• Barack to Business in 2009
  January 21, 2009
  At least for the biotech sector, change is certainly here.

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