Thursday, June 25, 2009
University of Illinois at Urbana-Champaign researchers are developing a new solid-state nanopore sensor that they believe can move the reality of fast and affordable genome sequencing a step closer. The sensor, made by drilling a tiny hole through a thin film of aluminum oxide, could ultimately prove capable of performing DNA analysis with a single molecule. This would offer tremendous possibilities for personalized medicine and advanced diagnostics, according to the scientists, who published their paper online April 14 in Advanced Materials.
During this week's podcast lead author Bala Murali Venkatesan provides additional details on the novel nanopore sensor and how it was manufactured. He talks about its advantages over its biological counterparts and describes how the nanopore sensor could lead to quicker and less expensive genome sequencing. Murali Venkatesan also discusses the experiments he and his team carried out to demonstrate the functionality of the sensor and addresses the issue of what still needs to be done to make the sensor a marketable product for genome sequencing.
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