Wednesday, March 18, 2009
John Sterling
Despite the recession and what seemed like a lower number of attendees than usual, there still was a positive buzz in the air at this week’s Interphex Conference in New York. A number of companies chose the venue to introduce novel products and technologies aimed at the biomanufacturing segment of the industry. Descriptions of several of these new market entrants follow.
Sensorin previewed what it calls the “world’s first continuously self-calibrating pH instrument.” Carolyn Kahn, Ph.D., company president and CEO, said the main advantage of the molecular electronic CSC sensor, which will be marketed in the fall, is that it does not drift, thus providing stable and continuously accurate pH measurement, she added. The result, continued Dr. Kahn, is lot-to-lot consistency and improved productivity.
Millipore launched four Mobius FlexReady® Solutions, which are composed of Flexware™ single-use filter assemblies and hardware systems designed for clarification, media and buffer preparation, tangential flow filtration, and virus filtration unit operations. According to Paul Chapman, vp of downstream processing at Millipore, the products were developed in response to consultations with customers seeking greater flexibility with different batch sizes, faster processing times, and more efficient unit operations.
Pall Corp. unveiled its Stax™ single-use depth filter platform. According to Pall’s Ian Selleck, the platform can be anchored to the floor or placed on casters so it can be moved. The Stax system is made up of interchangeable single-use depth filter capsules housed in a stainless steel chassis that can be managed by a single operator, explained Selleck. The product is scalable for lab, pilot, and process applications.
Capsule sizes (small-medium-large) allow for mix-and-match incremental increases in filter area (0.25 m² to 2.0 m² effective filtration area) throughout the modular design, said Selleck. The system is available in bottom in/top out and bottom in/bottom out configurations.
Pall also introduced Q and S HyperCel™ ion exchange sorbents, the Fluorodyne® EX grade EDT filter, and Allegro™ 1000 and 1500 liter 3D biocontainers.
The new Nalgene® Bioprocess Bag Management System is now available from Thermo Fisher Scientific. A company spokesperson said the system offers an organized method for managing flexible bags. A barrier, composed of a rigid polycarbonate shell top and bottom, protects a bioprocess bag.
The system contains a front compartment for storing tubing while the interior is contoured to fit commercially available bags. The system comes in clear (for sample viewing) and opaque (for protection against light) versions.
About a year-and-a-half ago, Alfa Laval launched in Europe the ART® Plate Reactor, which permits manufacturers to move from batch processing to continuous processing of chemicals, explained company spokesperson Tom Thane Nielsen. Interphex marked the debut of the ART Plate Reactor in the U.S. The product combines the properties of a continuous chemical reactor with those of a plate heat exchanger. According to Nielsen, it allows faster scale up, better yields, and improved control of the reaction.
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