Global Blood Therapeutics is a product-focused company building a pipeline of innovative, oral medicines to improve the treatment of chronic blood-based diseases and severe genetic disorders for which there are currently no cures available and only extremely limited therapeutic options. The company's unique SHAPE Platform is enabling the discovery and development of small molecule drugs that change the shapes of key blood proteins to modify their functions, enhance vital biological pathways and drive therapeutic benefits.

Gradalis is a privately-held, fully-integrated biotechnology company based in Dallas, Texas that is developing, manufacturing and commercializing drugs, vaccines, tools and diagnostics primarily in the area of cancer. The company has two platforms:  one focused on personalized autologous vaccines and the other  on bifunctional short hairpin RNA delivered via a proprietary lipoplex system. Recently-published data showed that FANG, the company’s autologous tumor vaccine, showed significant survival benefit in patients with advanced disease for multiple types of cancer. Gradalis has its own state of the art GMP manufacturing facility, as well as a strategic partnership with Mary Crowley Cancer Research Centers for early stage clinical development of Gradalis products.  

Helmedix, a start-up company from the ithree institute at the University of Technology Sydney, is a biopharmaceutical company developing therapies for autoimmune diseases based on peptides derived from a helminth parasite. Helmedix will be managed as a virtual company, based in Sydney, with research contracted to Dr Donnelly’s team at the ithree institute.

Hepregen's mission is to translate the value of its technology platform to improve the safety and efficacy of drugs in development with greater economic efficiency and significant impact on patients' lives. The company is focused on advancing and commercializing its microliver platform, HepatoPac™, into the drug-development pipeline of pharmaceutical and biotechnology companies. Hepregen's platform technology offers the potential to deliver a breakthrough technology for toxicity screening and a new platform for drug discovery.

HiberGene is developing a molecular diagnostic test for meningitis which can be used to test for the presence of the two most common forms of the disease, Meningococcus and Pneumococca. The test uses a rapid isothermal amplification platform allowing accurate results to be delivered in less than forty minutes. The company intends to develop a range of tests for a number of infectious human diseases including healthcare associated infections and sexually transmitted Infections.

Hookipa Biotech, founded in Vienna, Austria in summer 2011, develops a new class of innovative prophylactic and therapeutic vaccines. The Vaxwave® technology is a vaccine platform using a replication-defective viral vector for the prevention and treatment of multiple infectious diseases and cancer. The company currently focuses on the development of its lead vaccine candidate HB101 and plans to further industrialize the Vaxwave® technology and build a robust product pipeline. Hookipa has recently moved into its BSL2 facility at the Campus Vienna Biocenter.

ImmusanT is a privately-held biotechnology company focused on restoring tolerance to gluten in celiac disease by harnessing new discoveries in immunology that aim to improve diagnosis and treatment and return patients to a normal diet, good health and improved quality of life. The company is developing Nexvax2®, a therapeutic vaccine for celiac disease, and a companion diagnostic and monitoring tool to improve celiac disease management.

JB Therapeutics, a clinical stage biopharmaceutical company, is developing JBT-101 a nanomolar cannabinoid agonist which activates the CB2 receptor present on immune cells and fibroblasts. Upon binding CB2, JBT-101 stimulates the production of specific lipid mediators (PGJ2, LXA4) which act to turn off inflammation and fibrosis. The product is a pharmaceutical capsule containing a pure synthetic derivative of THC with minimal blood brain barrier penetration. It is currently being developed as a potential disease modifying treatment for the orphan disease scleroderma.

Kancera AB is a biotechnology company that focuses on the development and sale of drug candidates that have the potential to cure or to stop the progression of cancer. Kancera is currently running two pharmaceutical development projects, one relating to solid tumors and one relating to leukemia. Through a subsidiary, Kancera also provides big pharma, mid-sized pharma and biotech companies with lead identification and optimization services such as high-throughput screening (HTS), fragment-based screening (FBS), assay development and medicinal chemistry.

KemPharm is a development stage biopharmaceutical company focused on the discovery and development of new, safer therapies in the areas of pain, ADHD, and other CNS diseases. The company’s primary efforts include the development of safer abuse resistant opioid pain relievers. The company’s drug discovery and development platform is based on its proprietary Ligand Activated Therapy (LAT) approach. KemPharm uses its patent-applied technology to improve existing drugs and shorten the development timeline while still maintaining a strong intellectual property position within each therapeutic area.