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Nov 01, 2005 (Vol. 25, No. 19)

ZINC is not Commercial

  • Number of chemicals
  • Lack of clarity
Another one of those sites about which I say "hmmmm." ZINC is not Commercial is a site that Shakespeare might have advised, "Though doth protest too much." I guess being commercial is a risk when housing a database of commercially available compounds. As stated at the site, "ZINC contains over 3.3 million compounds in ready-to-dock, 3-D formats." Ready to dock? Binding of a ligand to a protein receptor, dummy. Another comment was more puzzling—ZINC provides "a free database of commercially available compounds for virtual screening." Virtual screening? I couldn't figure that one out. There appears to be a lot offered here, but the lack of descriptions and poor organization will leave most visitors wanting more. I certainly did.
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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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