Improving Human Health: The Promise of Epigenetics
A New Perspective for Genomic Research from Prof. Shankar Balsubramanian
Translating Innovation into Therapies
Antimicrobial Resistance and Drug Commercialization Were Key Topics at the Recent ON Helix Conference in Cambridge, U.K.
Literature Review: Dielectrophoresis to the Fore
Old Methodology Resurrected to Allow Inexpensive Label-Free Separation of Cell Populations
A Noninvasive Future
Prenatal Genetic Testing Looks to Single-Cell Methods as the Next Frontier
Vectors (plasmids, cosmids, BACs, etc.) are certainly friends to the researcher—we all use these valuable DNA constructs to clone and manipulate our DNA sequences of interest. But, what happens when (dun, dun, DUN!) vectors turn against us?! OK, so it’s not quite that dramatic, but it is true that vector contamination is a legitimate threat when it comes to sequencing your precious DNA of interest. So how can you be sure that a particular DNA sequence—be it your own or one that you found online—is free from contamination? The NCBI actually offers an online resource for exactly that purpose. VecScreen allows users to input a query sequence (via Accession number, GI, or FASTA sequence) and search it against an extensive database of vector sequences. The search tool subsequently identifies fragments that may be of vector origin.