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Sep 01, 2011 (Vol. 31, No. 15)

TM4 Microarray Software Suite

  • Good FAQ page
  • MADAM has limited compatibility

Microarray analyses of gene expression are incredibly useful because they generate a large amount of data. They are also somewhat of a hassle to deal with because, well, they generate a large amount of data. Thankfully, researchers at the Dana-Farber Cancer Institute are here to help us all out with TM4, a microarray software suite composed of (yes, you guessed it) four separate programs related to the collection and analysis of microarray data. And yes, all four programs are free to download. They include: MADAM (Microarray Data Manager, to load/retrieve data to and from a database), TIGR Spotfinder (for image processing), TIGR MIDAS (Microarray Data Analysis System, to process/normalize raw experimental data), and MeV (MultiExperiment Viewer, to analyze and identify gene-expression patterns). My only complaint is that MADAM only runs on Windows. The others are compatible with Windows-, Linux-, or Mac-based operating systems.

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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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