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Jan 15, 2005 (Vol. 25, No. 2)

The Pawson Lab: Researching Signal Transduction

URL:www.mshri.on.ca/pawson/domains.html
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Tony Pawson at Mount Sinai Hospital in Toronto put together an organized and well-written website on protein domains important for transcription factors. As noted at the site, one can characterize proteins involved in cellular communication/response as consisting of combinations of domains for interaction and catalysis. The opening page gives a simple schematic overview of the various domains. Clicking on icons brings up descriptions of what the domains do and which protein classes contain them. In addition, the opening page has an easy-to-understand discripton about domains in general that is worth a look. Since the information is not significantly hyperlinked to other sources, the site is not overly broad, but the descriptions make it an informative and educational place to visit.
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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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