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Nov 15, 2012 (Vol. 32, No. 20)

SuperTarget

URL:insilico.charite.de/supertarget
  • Many search options, good organization
  • Nothing major

You may feel as if you have super powers after visiting SuperTarget, a website whose name could double as a hero in a comic book series. The SuperTarget database is a great destination for researchers studying drug-target relationships, as it is primarily composed of three types of entries: drugs, proteins, and side effects. In addition to providing site visitors with the options of searching by drug or target, SuperTarget also includes the ability to search for KEGG pathway maps, as well as the option to perform an ontology search (either by molecular function, cellular component, or biological process). If your proteins of interest happen to be in the Cytochrome P450 family then you are especially in luck, as the site includes an entire section devoted to this target class.

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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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