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Jun 01, 2011 (Vol. 31, No. 11)


  • Great site design, many aspects of database
  • "Help/Info" page down

If, as the saying goes, “a stitch in time saves nine,” then a visit to STITCH2 online saves nine postdocs time. STITCH2 is a wonderful website to explore the interactions (both known and predicted) between proteins and chemicals. This site is a dream for anyone who enjoys exploring databases—there are five different search options (by name, chemical structure, protein sequence, multiple names, or multiple sequences) and 630organisms from which to choose. In total, the database includes interactions for more than 2.5 million (yes, million!) proteins and more than 74,000 small molecules. The search results are beautifully displayed as network diagrams in which one can click on each node for more information. Importantly, there are multiple viewing options. With the confidence view for example, stronger associations are represented with thicker lines. In evidence view, different colors denote various types of evidence for the associations.

  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good

*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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