Leading the Way in Life Science Technologies

GEN Exclusives

More »

Best of the Web

More »
Sep 01, 2007 (Vol. 27, No. 15)

spliceNest

URL:splicenest.molgen.mpg.de
  • Great EST tool
  • Is a bit dated
Before there were genomic sequences, there were ESTs, which served as mileposts on the nucleic acid superhighway and, by golly, they were good. ESTs of course are sequence segments of random cDNAs and as such are exons of genes. ESTs proved to be excellent tools for both helping to clone and sequence full length cDNAs as well as for identifying gene transcripts and discovering genes. At spliceNest, one will find databases devoted to providing researchers access to EST information. Options include searching by chromosome number, cluster search, keyword, or sequence (BLAST) or one can simply browse by clicking on a chromosome icon and selecting from a list of ESTs. The retrieved information includes graphics with genomic sequence alignments, exon/intron structure, and possible alternative splice sites.
  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good


*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »