Leading the Way in Life Science Technologies

GEN Exclusives

More »

Best of the Web

More »
Jan 15, 2013 (Vol. 33, No. 2)

SMART

URL:smart.embl-heidelberg.de
  • Includes glossary, two different operating modes
  • No user guide

If you are interested in studying protein domains—their phyletic distributions, functional class, important amino acid residues, etc.—then it would be a “smart” move to visit the website for the Simple Modular Architecture Research Tool (SMART). Originally described in a 1998 publication, this tool is still very actively updated, with the most recent publication related to SMART being published this year. Through its ability to identify modular domains from user-inputted protein sequences or sequence IDs, SMART is a great tool for scientists interested in the analysis of protein domain architecture. SMART can be used in two modes: normal or genomic. Whereas the normal mode includes various proteome sources in its database, the genomic mode only includes the proteomes of completely sequenced genomes. The site includes a glossary to familiarize users with some of the jargon they might encounter when using SMART, such as “HMM consensus” and “seed alignment.”

  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good


*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

Be sure to take the GEN Poll

Drug Price Hikes

Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?

More »