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Aug 01, 2011 (Vol. 31, No. 14)

PRIDE

URL:www.ebi.ac.uk/pride
  • Very large database, free data-analysis application
  • None

The European Molecular Biology Laboratory (EMBL) has done it again—they have developed another database of which they can be “proud.” PRIDE is quite literally the name of the game when it comes to this proteomics database, whose full name is the PRoteomics IDEntifications database. Containing more proteomics data than a single person could ever sort through in his/her entire career, the PRIDE database houses over 16,000 experiments, over 145 million (yes, million!) MS spectra, and more than 24 million identified peptides. Users of the database can either search its contents or browse by a number of categories, such as species, cell type, or disease. Additionally, the site recently made the PRIDE Inspector available for download. This application allows one to browse, visualize, and analyze MS proteomics data. This database is a fantastic resource for proteomics researchers.

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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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